WP3: Musculoskeletal Structure

This WP (leader: Dr. Rittweger) will assess changes in muscle function, muscle volume, and changes in muscle ultra-structures like mitochondrial function.  This WP also includes measuring changes in bone structure before and after the hypoxia bedrest interventions.

OBJECTIVES

1: measure muscle volume, strength and power (see WP1 for muscle strength)

2: quantify muscle ultra-structure and metabolic function (see also WP5 for metabolic function)

3: measure changes in bone mass and geometry

4: assess changes in biochemical markers of bone metabolism

Image: an example of osteoporosis in bone.